GE Healthcare also introduced Process Characterization Kits to its catalog in July 2019. Chromatography process characterization kit MabSelect PrismA, MabSelect SuRe, MabSelect SuRe LX, Capto S ImpAct, Capto Q, Capto SP ImpRes, and Capto Adhere prepacked resins are available for use with these columns. The columns come equipped with a bed height of 20 cm and an inner diameter of 10 mm. The columns can be run on chromatographic systems, including the company’s own ÄKTA chromatography systems, and are prepacked to save time, improve reproducibility, and eliminate the need for packing expertise, the company says. Validation columns from GE Healthcare involve pre-packed scale down Tricorn 10/200 columns for process development and process validation. The column is compatible with a variety of chromatography resins including those used for monoclonal antibody (mAb) purification, viral vectors, plasmids, recombinant proteins, and more. Introduced to the market in July 2019, the ReadyToProcess 600 mm inner diameter chromatography column comes equipped with bed heights of 100–250 mm.
The pre-packed, ready-to-use column offers enhanced flexibility and productivity in clinical and commercial manufacturing by eliminating the need for column preparation, packing, and validation procedures, according to the company. The ReadyToProcess chromatography column with 600 mm inner diameter is the latest addition to the ReadyToProcess chromatography column line from GE Healthcare. The following products promise to improve and enhance the reliability of process chromatography. Advances in process chromatography are necessary for accuracy and productivity in biologics manufacturing.
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